SmartEnzymes™ for the Glycosylation Charcterization of Glycoproteins
Scientific Poster
Enzymatic Tools for the Structural Characterization of Glycoproteins | EMBO Workshop (2024)
Related Products
ImpaRATOR™ Lyophilized
Lyophilized enzyme for digestion of mucin-type O-glycoproteins and peptides, including sialylated O-glycan species
Related Applications
Combining multiple digestions for O-glycan site mapping with glycan structure analysis for complete characterization of heavily O-glycosylated proteins.
Broad O-glycan substrate acceptance efficiently generating informative O-glycopeptides while retaining glycan structure information.
Selective removal of α1-2/3/4 fucose for more comprehensive N- and O-glycan characterization.
Removal of glycan β-galactose to simplify IgG glycan heterogeneity, improve LC-MS analysis, and reveal underlying glycation modifications.
Confirmation and quantification of Tn antigens on O-glycosylated biopharmaceuticals while simplifying intact-mass analysis and revealing protein variants.
O-glycan site occupancy profiling and complete deglycosylation of etanercept for in-depth characterization of complex O-glycoproteins.
Efficient removal of core 1 O-glycans from complex glycoproteins to reduce heterogeneity and improve mass spectrometry characterization.
Complete desialylation of complex glycoproteins to simplify glycan profiles and enable more confident protein characterization.
