Applications

Here you find information about how you can use Genovis' products in your application.

The Enzyme Reference Tool organizes all papers published using our products. With this tool you can filter by quality attribute, enzyme used, type of antibody molecule and technology.

Enzyme Reference Tool

/Reference_tool_220px.pngThe Enzyme Reference Tool organizes all papers published using our products. With this tool you can filter by quality attribute, enzyme used, type of antibody molecule and technology.

IgG Protease Digestion Chart

With the IgG protease digestion chart you can see the digestion site of Genovis' enzyme and what species and subclass of antibody the enzyme will digest.

Species & Subclasses FabRICATOR®
Native IgG
FabULOUS®
Digestion under reduced condition.
* Primary digestion site.
GingisKHAN®
Native IgG
Human IgG1 ..CPAPELLG / GPSVF.. ..KTHT / CPPCPAPEL..* ..KSCDK / THTCPPCP..
Human IgG2 ..CPAPPVA / GPSVF.. Yes (Site N.D.) X
Human IgG3 ..CPAPELLG / GPSVF.. Yes (Site N.D.) Multiple sites in Fc
Human IgG4 ..CPAPELLG / GPSVF.. X X
Mouse IgG1 X ..KPCIC / TVPEVS.. X
Mouse IgG2a ..CPAPNLLG / GPSVF.. Yes (Site N.D.) X
Mouse IgG2b X Yes (Site N.D.) X
Mouse IgG3 ..CPPGNILG / GPSVF.. Yes (Site N.D.) X
Rat IgG2b ..CPVPELLG / GPSVF.. Yes (Several sites) N.D.
Rhesus Monkey ..CPAPELLG / GPSVF.. N.D. N.D.
Rabbit ..CPPPELLG / GPSVF.. ..KPT / CPPPE..* N.D.

X = no digestion confirmed
N.D. = Not determined