GalNAcEXO®
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Lyophilized enzyme for hydrolysis of GalNAc residues on glycoproteins

GalNAcEXO is an α-N-Acetylgalactosaminidase for efficient hydrolysis of terminal GalNAc residues on glycoproteins.
GalNAcEXO Lyophilized is available as a lyophilized powder in 2000 unit vials for hydrolysis of GalNAc residues on 2 mg glycoprotein.
Lyophilized enzyme for hydrolysis of GalNAc residues on 2 mg glycoprotein

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One unit of GalNAcEXO Lyophilized catalyzes the hydrolysis of α-linked GalNAc residues from ≥ 95% of 2 nmol 4-Nitrophenyl 2-acetamido-2-deoxy-D-galactopyranoside when incubated in 20 mM Tris, 1 % ethanol pH 6.8 at 37°C for 30 minutes, as monitored by reversed-phase chromatography.
GalNAcEXO Lyophilized is reconstituted by addition of water. No preservatives added. After reconstitution, GalNAcEXO Lyophilized is stable for 1 month at +4-8°C. The product is shipped cold and should be stored at -20°C upon arrival.
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Confirmation and quantification of Tn antigens on O-glycosylated biopharmaceuticals while simplifying intact-mass analysis and revealing protein variants.
O-glycan site occupancy profiling and complete deglycosylation of etanercept for in-depth characterization of complex O-glycoproteins.
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