Efficient Fab generation for SPR-based separation of affinity and avidity effects, supporting detailed functional characterization of monoclonal antibodies.
Bioanalytical
Bioanalytical workflows support the quantification and characterization of biomolecules in complex biological samples such as human serum. These analyses are essential for understanding pharmacokinetics, immunogenicity, and therapeutic performance. Our SmartEnzymes™ enable efficient and reproducible sample preparation, helping you generate reliable data from challenging matrices.
Applications
Selective enrichment of O-glycoproteins from human serum for improved LC-MS/MS detection and glycosylation-focused proteomic analysis.
Isotype-specific digestion of IgM and IgG in serum, allowing simultaneous analysis without enzymatic cross-interference.
Subclass selective digestion of IgA in complex samples like serum, enabling targeted analysis of IgA1 and IgA2m1 without off-target cleavage.
