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FabRICATOR® (IdeS)
Below hinge digestion of IgG
FabALACTICA® (IgdE)
Above hinge digestion of human IgG1
FabDELLO™
Above hinge digestion of human IgG1
FabRICATOR® Z (IdeZ)
Below hinge digestion of mouse IgG
GingisKHAN® (Kgp)
Above hinge digestion of human IgG1
FabULOUS™ (SpeB)
Above hinge digestion of IgG
GlySERIAS™
Hydrolysis of Flexible Linkers
GlyCLICK®
Site-specific conjugation of IgG
TransGLYCIT™
Transglycosylation of IgG
GingisREX® (RgpB)
Arginine-specific protein digestion
OmniGLYZOR™
Hydrolysis of N- and mucin-type O-glycans
PNGase F
Hydrolysis of N-glycans
OpeRATOR®
O-glycan specific protein digestion
OglyZOR®
Hydrolysis of core-1 O-glycans
SialEXO®
Hydrolysis of sialic acids
FucosEXO™
Hydrolysis of α1-2,3,4 fucose
GalactEXO™
Hydrolysis of β1-3,4 galactose
GalNAcEXO™
Hydrolysis of α-linked GalNAcs
GlycOCATCH®
Enrichment of O-glycopeptides
GlycINATOR® (EndoS2)
Hydrolysis of all Fc N-glycans
IgGZERO® (EndoS)
Hydrolysis of Fc N-glycans
Anti-FabRICATOR®
Detection of the FabRICATOR® enzyme
Anti-FabRICATOR® Z
Detection of the FabRICATOR® Z enzyme
Antibody LC-MS Analysis
Fast LC-MS profiling of antibodies
Antibody Fragmentation
Digestion and analysis
Antibody Conjugation
Conjugation and analysis
Custom Antibodies
Antibody development, production and purification
SmartEnzymes for Biopharmaceuticals
The SmartEnzymes portfolio consists of enzymatic products and technologies designed to improve the efficacy and throughput in analytical or preparative workflows for complex biopharmaceuticals such as antibodies, Fc-fusion proteins, complex glycoproteins or antibody conjugates.
Learn more about our products and services!
Applications for SmartEnzymes
Whether you are working with research and development or routine quality control of biopharmaceuticals, our products are designed to deliver the best results in the most efficient way.
Find your application and the SmartEnzymes that suit your project in an online meeting together with our enzyme experts!
Resources - Find out more
Interested in more applications or which SmartEnzymes to use in your project? We share a wide range of resources including posters, application notes and brochures that showcase our variety of product formats and the different applications for SmartEnzymes.
References Highlights
- Challenges and Strategies for a Thorough Characterization of Antibody Acidic Charge Variants
2022-11-03
Y. Diana Liu , Lance Cadang, Karenna Bol, Xiao Pan, Katherine Tschudi, Mansour Jazayri, Julien Camperi , David Michels, John Stults, Reed J. Harris and Feng Yang - A Combination of Native LC-MS Approaches for the Comprehensive Characterization of the Antibody-Drug Conjugate Trastuzumab Deruxtecan
2022-10-26
Evolène Deslignière, Hélène Diemer, Stéphane Erb, Pierre Coliat, Xavier Pivot, Alexandre Detappe, Oscar Hernandez-Alba, Sarah Cianférani - A universal glycoenzyme biosynthesis pipeline that enables efficient cell-free remodeling of glycans
2022-10-24
Thapakorn Jaroentomeechai, Yong Hyun Kwon, Yiwen Liu, Olivia Young, Ruchika Bhawal, Joshua D. Wilson, Mingji Li, Digantkumar G. Chapla, Kelley W. Moremen, Michael C. Jewett, Dario Mizrachi & Matthew P. DeLisa