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Site-specific conjugation of native antibodies

Enzymes for O-glycans

Site-specific O-glycan analysis using the new OpeRATOR® protease


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IgG Glycosidases

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Enzymes for Biopharmaceuticals

Genovis provides unique enzymes and technologies for analytical characterization and conjugation of biopharmaceuticals. The SmartEnzymes™ portfolio consists of FabRICATOR® (IdeS), FabRICATOR®Z (IdeZ), FabALACTICA® (IgdE)FabULOUS® (SpeB), GingisKHAN® (KGP), GingisREX® (Rgp), IgGZERO® (EndoS)GlycINATOR® (EndoS2), OpeRATOR®, GlycOCATCH™OglyZOR®, SialEXO® and the antibody conjugation technology GlyCLICK®.


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2019-12-10: New product! Immobilized SialEXO®

Immobilized SialEXO is a microspin column for complete removal of sialic acids from native glycoproteins in 30 minutes. No enzyme in the final preparation!

2019-10-08: Genovis Launches GlyCLICK® 2 mg

GlyCLICK is a site-specific conjugation technology for IgG using enzymatic remodeling of the Fc-glycans and click-chemistry. The GlyCLICK technology is available in a range of kit formats to facilitate tailored and site-specific labeling of antibodies. GlyCLICK for azide activation of 2 mg of antibody is available for purchasing today.

2018-04-26: Genovis Launches GlycOCATCH™

GlycOCATCH is an enrichment resin for affinity purification of O-glycosylated proteins and peptides. The resin is designed to bind proteins and peptides carrying O-glycans with high affinity, and it is provided in convenient spin columns to allow easy-to-use O-glycoprotein enrichment. The GlycOCATCH product is available for purchasing today.

Antibody Glycation Study using Intact LC-MS 

IgGZERO is starring a newly published study demonstrating the use of intact mass spectrometry to determine the level of glycation on therapeutic antibodies. To perform the assay, IgGZERO was used to rapidly remove the Fc-glycans.

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IgG Cleavage

IgG Proteases

Specific digestion of IgG with activity on human IgG1-4 as well as other species



Learn more about the applications of Genovis SmartEnzymes for mass-spectrometry analysis of antibodies, antibody oxidation assay and more.

Smart Enzyme Reference Tool

SmartEnzyme Reference Tool

Find the right reference for the antibody attribute you are studying

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