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Site-specific conjugation of native antibodies 


Enzymes for O-glycans

Site-specific O-glycan analysis using the new OpeRATOR™ protease

Investor Relations

Investor Relations

Financial Reports and Press Releases

IgG Glycosidases



Genovis provides unique enzymes and technologies for analytical characterization and conjugation of biopharmaceuticals. The SmartEnzymes™ portfolio consists of FabRICATOR® (IdeS), FabRICATOR®Z (IdeZ), FabALACTICA™ (IgdE)FabULOUS® (SpeB), GingisKHAN® (KGP), GingisREX™ (Rgp), IgGZERO® (EndoS)GlycINATOR® (EndoS2), OpeRATOR™, OglyZOR™, SialEXO™ and the antibody conjugation technology GlyCLICK™.


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A New Assay to Study Antibody Disulphide Bonds using FabRICATOR and FabALACTICA

In a recently published article, FabRICATOR was used to digest below the hinge and FabALACTICA above the hinge of human IgG1, generating three fragments; the hinge peptide, the Fab and the Fc/2 fragments. This setup enables analysis of both inter- and intrachain disulphide bonds, as well as other quality attributes.

Genovis launches Immobilized FabALACTICA and FabALACTICA Fab Kit

Immobilized FabALACTICA digests above the hinge of human IgG1 and generates intact Fab and Fc fragments without reducing conditions. FabALACTICA Fab Kit purifies intact and pure Fab fragments and does not require optimization.

Presentation of OpeRATOR™ at PEGS Europe in Lisbon

The poster abstract on OpeRATOR for site-specific O-glycan analysis was selected for an oral presentation at the PEGS meeting in Lisbon.

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IgG Cleavage

IgG Proteases

Specific digestion of IgG with activity on human IgG1-4 as well as other species


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Smart Enzyme Reference Tool

SmartEnzyme Reference Tool

Find the right reference for the antibody attribute you are studying



Products for rapid and specific characterization of biopharmaceuticals



Learn more about the applications of Genovis SmartEnzymes for mass-spectrometry analysis of antibodies, antibody oxidation assay and more.

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