Our SmartEnzymes™ Portfolio
Genovis SmartEnzymes portfolio consists of IgG Proteases, IgG Glycosidases, Enzymes for O-Glycans, Exoglycosidases and Conjugation.
Nature offers a vast source of enzymes, perfected through evolution to perform defined reactions. At Genovis, we believe that enzymes with unique properties can be used as biological tools to support the research and development of complex biopharmaceuticals to help bring safe and effective medicines to patients in need. Our task is to identify new enzymes and give them names.
We call them SmartEnzymes.
IgG PROTEASES
Our IgG Proteases SmartEnzymes portfolio consists of FabRICATOR® (IdeS protease), FabRICATOR®Z (IdeZ), FabALACTICA® (IgdE), FabULOUS™ (SpeB), GingisKHAN® (KGP).
The general protease GingisREX® (RgpB) is also included. The enzymes are applied in analytical workflows of biotherapeutic proteins, including antibody subunit analysis using liquid chromatography and mass spectrometry.
More information can be found on our Applications page or by downloading our Applications notes or Posters.
IgG GLYCOSIDASES & CONJUGATION
The Genovis product line of IgG Glycosidases and Conjugation consists of IgGZERO® (EndoS), GlycINATOR® (EndoS2) and GlyCLICK® (Conjugation).
More information can be found on our Applications page or by downloading our Applications notes or Posters.
SmartEnzymes for O-glycans & EXOglycosidases
The Genovis product line of enzymes for O-glycans consists of OpeRATOR® (O-glycan-specific protease), GlycOCATCH® (enrichment resin for O-glycosylated proteins and peptides), and OglyZOR® (O-glycosidase). The recently launched EXOglycosidases include GalactEXO (galactosidase), GalNAcEXO (exo-α-N-Acetylgalactosaminidase) and SialEXO® (sialidase).
More information can be found on our Applications page or by downloading our Applications notes or Posters.
Services
We offer services for your antibody fragmentation project. In addition to our in-house produced SmartEnzymes product portfolio, we also use other classic enzymes in our service. Moreover, we have extensive experience purifying and analyzing the final fragments.