SmartEnzymes™ for Highly Efficient Bottom-up Proteomics
Scientific Poster
Performance Characterization of a Recombinant Protease Platform for Bottom-up Proteomics | Festival of Biologics (2026)

Related Products
TrypsINATOR™ LysCERATOR Mix Lyophilized
Lyophilized enzyme mix for arginine- and lysine-specific protein digestion

Related Applications
Enhanced cleavage at challenging K–P sites, reducing missed cleavages and enabling more complete, confident peptide identification.
High efficiency and peptide coverage maintained in strong denaturants, supporting analysis of highly structured and aggregation-prone proteins.
Consistent proteolytic activity delivered with no detectable autoproteolysis, enabling cleaner LC–MS data and more confident peptide identification.
Efficient peptide mapping of antibodies with minimal missed cleavages and high sequence coverage for confident PTM identification.
Superior digestion efficiency with high lysine specificity, generating more unique peptides for confident protein identification in complex proteomics workflows.
Improved digestion efficiency at challenging K–P sites compared to TrypsINATOR alone, resulting in more complete digestion with fewer missed cleavages.
Efficient digestion with minimal missed cleavages and high sequence coverage resulting in efficient peptide mapping and confident protein characterization.
Highly specific lysine and arginine digestion with more unique peptides and fewer missed cleavages for confident protein identification in complex proteomics workflows.
Robust digestion performance with limited autoproteolysis, enabling cleaner LC–MS data and more confident peptide identification.





