GingisKHAN enzyme is a unique protease that digests human IgG1 between K223 and T224 producing a homogenous pool of Fab and Fc fragments. The enzyme requires only mild reduced condition for activity and the reaction is performed in the presence of 2 mM Cystein at neutral pH, leaving intact Fab and Fc fragments.
- Specific - one precise cleavage site in upper hinge of human IgG1
- Rapid – 60 minute protocol for complete digestion
- Comes with ready to use reaction buffer additive for convenient and reliable performance
GingisKHAN enzyme supplied as lyophilized powder together with 5 vials of lyophilized GingisKHAN reducing agent for convenient and reliable performance. The enzyme is available in 2000 unit vial (1 unit digest 1 ug IgG).
GingisKHAN® Fab kit
GingisKHAN Fab kit is used for rapid and easy preparation and purification of of Fab fragments from human IgG1 antibodies. The kit consists of two parts; lyophilized GingisKHAN enzyme and affinity spin columns for purification of intact Fab fragments.
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The trademark GingisKHAN is the property of Genovis AB.
For research use only. Not intended for any animal or human therapeutic diagnostic use.
©2016 Genovis AB.