GlySERIAS®
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GlySERIAS® Immobilized
Immobilized enzyme for digestion of fusion proteins in spin columns
GlySERIAS is a unique enzyme that digests flexible glycine-rich fusion protein linkers such as Gly4Ser and GlyxSery (GS), and polyglycine (G) linkers.
The GlySERIAS Immobilized spin columns contain GlySERIAS enzyme covalently coupled to agarose beads, for digestion of fusion proteins without enzyme in the final preparation. The Microspin columns are available for digestion of 5 or 10 x 0.2 mg fusion protein.
Why GlySERIAS® Immobilized?
- Easy-to-use spin columns
- Increased enzyme-to-substrate ratio for improved digestion efficiency
- No enzyme in the final sample
- Improved linker removal
Available Products
GlySERIAS® Immobilized Microspin 5 x 0.2 mg
Immobilized enzyme for digestion of 5 x 0.2 mg fusion protein in spin columns
GlySERIAS® Immobilized Microspin 10 x 0.2 mg
Immobilized enzyme for digestion of 10 x 0.2 mg fusion protein in spin columns
For information on how to order, visit Place an Order or contact us directly at order@genovis.com.
Product Information
Activity
One Microspin column contains sufficient GlySERIAS-coupled agarose beads to digest 0.2 mg fusion protein.
Content and Storage
GlySERIAS Immobilized is supplied in 20% ethanol, shipped cold, and should be stored at +4-8°C upon arrival. Do not freeze the product!
Resources
Instruction for Use
Product Specifications
Safety Data Sheet
Certificate of Analysis
Find your certificate of analysis »AppNote GlySERIAS® for Digestion of Flexible Linkers of Fusion Proteins
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GlySERIAS® for LC-MS Analysis of Fusion Proteins with Flexible Linkers
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Applications
GlySERIAS Immobilized delivers a more complete digestion of linkers for precise characterization of fusion protein quality attributes.
Efficient digestion of multi-domain BiTE molecules, separating the domains for high-quality LC-MS analysis and precise localization of protein modifications
Legal & Disclaimers
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Genovis products are intended for research use only. They are not intended to be used for therapeutic or diagnostic purposes in humans or animals. All goods and services are sold subject to Genovis’ General Terms and Conditions of Sale.
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