Launching New Anti-FabRICATOR Formats!

May 7, 2021 | New Product, News |

We are happy to announce two new affinity purified antibody formats for detecting the FabRICATOR enzyme!
The Anti-FabRICATOR Affinity Purified is an affinity purified goat polyclonal antibody and
the Anti-FabRICATOR Affinity Purified Biotin Conjugated is an affinity purified and biotin-conjugated goat polyclonal antibody.

Anti-FabRICATOR (Anti-IdeS) detects the FabRICATOR enzyme (IdeS), a unique enzyme digesting IgG at a specific site below the hinge region. It is used in IHC, Western blot and ELISA assays, as well as in preclinical gene therapy applications (Leborgne et al., 2021).

To display the difference in performance between the Anti-FabRICATOR Protein G Purified product and the new Anti-FabRICATOR Affinity Purified, wells were coated with either Anti-FabRICATOR Protein G Purified or Anti-FabRICATOR Affinity Purified at 2 µg/ml. The FabRICATOR enzyme was added in dilutions from 1 µg/ml to 1 ng/ml. Anti-FabRICATOR Affinity Purified Biotin Conjugated was added at 1µg/ml. HRP-Streptavidin was added in a 1:2000 dilution.




Anti-FabRICATOR – Detects the FabRICATOR enzyme in a variety of applications.