Anti-FabRICATOR(R)

Anti-FabRICATOR® (Anti-IdeS)

Anti-FabRICATOR (Anti-IdeS) is a goat polyclonal antibody detecting the FabRICATOR enzyme.
 
Anti-FabRICATOR is available in three formats; affinity purified, biotin-conjugated affinity purified and purified on protein G. Anti-FabRICATOR can be used to detect the FabRICATOR (IdeS) enzyme in Western blot and ELISA assays, as well as in preclinical gene therapy applications.

Detailed Information

Anti-FabRICATOR detects the FabRICATOR (IdeS) enzyme, a unique enzyme that digests IgG at a specific site below the hinge region, generating a homogenous pool of F(ab')2 and Fc/2 fragments. FabRICATOR has no other known substrate besides IgG, and is cloned from Streptococcus pyogenes and expressed in E. coli.
 
Anti-FabRICATOR Affinity Purified is an affinity purified goat polyclonal antibody using FabRICATOR as the antigen. It is supplied as a frozen solution of 100 µl with a concentration of 1 mg/ml, with no preservatives added.
 
Anti-FabRICATOR Affinity Purified Biotin Conjugated is an affinity purified, biotin-conjugated goat polyclonal antibody using FabRICATOR as the antigen. It is supplied as a frozen solution of 100 µl with a concentration of 0.5 mg/ml, with no preservatives added.
 
Anti-FabRICATOR Protein G Purified is a protein G-purified goat polyclonal antibody. It is supplied as a frozen solution of 100 µl with a concentration of 4 mg/ml, with no preservatives added.
 

Storage and Stability

The antibodies are stable for at least five (5) years after production date when stored at -20°C to -70°C. Store the product in appropriate aliquots to avoid freeze-thaw cycles.

To display the difference in performance between the Anti-FabRICATOR Protein G Purified and the Anti-FabRICATOR Affinity Purified, wells were coated with either Anti-FabRICATOR Protein G Purified or Anti-FabRICATOR Affinity Purified at 2 µg/ml. The FabRICATOR enzyme was added in dilutions from 1 µg/ml to 1 ng/ml. Anti-FabRICATOR Affinity Purified Biotin Conjugated was added at 1µg/ml. HRP-Streptavidin was added in a 1:2000 dilution.

  • A3-AF2-010

    Anti-FabRICATOR Affinity Purified

    A3-AF2-010630.00Add to cart
  • A3-AF3-005

    Anti-FabRICATOR Affinity Purified, Biotin Conjugated

    A3-AF3-005750.00Add to cart
  • A3-AF1-010

    Anti-FabRICATOR Protein G Purified

    A3-AF1-010280.00Add to cart

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Genovis products are intended for research use only. They are not intended to be used for therapeutic or diagnostic purposes in humans or animals.

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