Antibody LC-MS Analysis Service from Genovis!

October 22, 2022 | New Product, News, Products |

We offer fast and accurate LC-MS profiling of human IgG using unique sample preparation based on SmartEnzymes workflows. Our SmartEnzymes enable middle-level LC-MS analysis of antibodies to characterize critical quality attributes such as the glycosylation profile and mass confirmation.

The quality of an antibody may affect the performance and eventually the clinical efficiency of a therapeutic drug. For this reason, antibody quality is studied early in therapeutic development and the industry is pushing to characterize critical quality attributes such as glycosylation and mass confirmation as early as possible. Our SmartEnzymes enable middle-level LC-MS analysis of antibodies to characterize critical quality attributes such as:

  • Mass confirmation
  • Glycosylation profile (%)
  • Afucosylation (%)
  • High-mannose (%)
  • C-terminal lysine (%)
  • N-terminal pyroglutamate (%)

With the Antibody LC-MS Analysis service, we provide sample preparation and LC-MS analysis to enable faster antibody quality data to scientists across the world. After receiving the antibody sample, the LC-MS analysis is performed and results are delivered within five days. The antibody quality data is presented in an easy-to-interpret report, with an overview for the unexperienced user and a more in-depth view for experienced users.

Why LC-MS Analysis Service from Genovis?

  • High-quality mass spectrometry data on critical quality attributes
  • Fast turnaround time –  results delivered within five working days
  • Unique and easy SmartEnzyme workflows performed by our expert MS team

How it Works


 
1. Contact us and share some specifics about your antibody to our MS experts. Send us your antibody sample (>100 ug).
 
2. We will apply our unique SmartEnzymes sample preparation workflows and perform the LC-MS analysis using high-quality instrumentation.
 
3. Within five working days, you will receive a detailed, easy-to-interpret, LC-MS analysis report containing the antibody quality attributes.
 
Contact us for more information!