FabDELLO® for the Analysis of Bispecific Chain Pairing
Scientific Poster
Characterization of Bispecific Antibody Chain Pairing Variants by LC-MS at the Subunit Level | PEGS Europe (2022)

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Above hinge digestion at a single lysine residue, producing defined fragments for robust LC-MS analysis of LALA-engineered IgG1 antibodies.
Improved characterization of bispecific antibody chain mispairing by FabDELLO subunit digestion and LC-MS resolution of Fab variants.


