Efficient digestion with minimal missed cleavages and high sequence coverage resulting in efficient peptide mapping and confident protein characterization.
Peptide Mapping
Peptide mapping is a powerful analytical technique involving the digestion of proteins into smaller peptides for detailed sequence and modification analysis. It is a well-established method for confirming protein identity and assessing critical quality attributes. Our tools support efficient digestion and peptide generation for high-quality and reliable mass spectrometry results.
Applications
Improved digestion efficiency at challenging K–P sites compared to TrypsINATOR alone, resulting in more complete digestion with fewer missed cleavages.
Robust digestion performance with limited autoproteolysis, enabling cleaner LC–MS data and more confident peptide identification.
Arginine-specific peptide mapping with improved perfomance over Arg-C, generates larger peptides complementary to trypsin.
Efficient peptide mapping of antibodies with minimal missed cleavages and high sequence coverage for confident PTM identification.
Enhanced cleavage at challenging K–P sites, reducing missed cleavages and enabling more complete, confident peptide identification.
Resources
SmartEnzymes™ Brochure
Download Product Folder
