How FabRICATOR® works

Benefits of Middle-level Analysis of Antibodies using FabRICATOR®

Performance Activity

Generation of defined IgG subunits via single-site, below hinge cdigestion, enabling high-resolution middle-level LC-MS and improved PTM characterization.

Preparation of F(ab’)2 and Fc Fragments using FabRICATOR®

Performance Activity

Generation and purification of F(ab’)2 and scFc fragments without residual enzyme, enabling rapid preparation of antibody fragments for downstream applications.

Rapid Determination of Fc Oxidation using FabRICATOR® and GlycINATOR™

Application

Fast and reliable middle-level analysis of antibody oxidation using FabRICATOR and GlycINATOR, supporting robust QC of critical quality attributes.