TransGLYCIT

995.00

Glycan remodeling of up to 1 mg of human IgG with G0, G1, G2 or G2S2.

995.00
995.00
995.00
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Description

TransGLYCIT contains all material needed to perform glycan remodeling of up to 1 mg of human IgG with the G0, G1, G2 or G2S2 glycoform.

Detailed Information

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FAQs

Unfortunately no, the enzyme requires trimming of the Fc-glycan using GlycINATOR to enable access to the core fucose substrate.

Yes, the transglycosylation reaction can be performed on all subclasses of human IgG. The reaction is somewhat slower on IgG2 and longer incubation times may be necessary to obtain over 95% transglycosylation.

No, TransGLYCIT is based on IgG specific enzymes and will only transglycosylate IgG.

The TransGLYCIT platform is developed for transglycosylation of human IgG.

GlycINATOR is an IgG specific endoglycosidase that hydrolyzes complex, hybrid and high mannonse type glycans on the conserved Fc site on IgG.

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