Site-specific ADC generation with defined DAR, preserving antigen binding and delivering potent, controlled cytotoxicity in target cells.
ADC Development
Antibody-drug conjugates (ADCs) combine targeted antibody specificity with potent cytotoxic payloads, requiring careful control and characterization. Analysis of conjugation, drug-to-antibody ratio (DAR), and structural integrity is essential throughout development. Our SmartEnzymes™ support in-depth and reliable ADC characterization, while GlyCLICK® enables site-specific conjugation for controlled ADC generation.
Applications
Resources
GlyCLICK® for Generation of Improved ADCs
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GlyCLICK® for Dual-payload ADCs
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GlyCLICK®
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GlyCLICK® for Generation and Analysis of ADCs
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PNGase F for Improved DAR Determination in Randomly Conjugated ADCs
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