FucosEXO®
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FucosEXO is a mix of α-Fucosidases for efficient hydrolysis of α1-2, α1-3 and α1-4-linked fucose residues on native N- and O-glycosylated proteins or free oligosaccharides.
FucosEXO Lyophilized is available as a lyophilized powder in 2000 unit vials for defucosylation of 2 mg glycoprotein.
Why FucosEXO® Lyophilized?
- Flexible format for method development
- Possible to combine enzymes for improved efficiency
- Amenable to automated workflows
- Ready to use – just add water!
Available Products
FucosEXO® Lyophilized 2000 units
Lyophilized enzyme for defucosylation of 2 mg glycoprotein
For information on how to order, visit Place an Order or contact us directly at order@genovis.com.
Product Information
Unit Defintion
One unit of FucosEXO Lyophilized hydrolyzes fucoses from ≥90% of 11 nmol 2′-fucosyllactose and 4.5 nmol 3-fucosyllactose when incubated in 20 mM Tris pH 6.8 at 37°C for 30 min.
Content and Storage
FucosEXO Lyophilized is reconstituted by addition of water. No preservatives added. After reconstitution, FucosEXO Lyophilized is stable for 1 month at +4-8°C. The product is shipped cold and should be stored at -20 °C upon arrival.
Resources
Instruction for Use
Product Specifications
Safety Data Sheet
Certificate of Analysis
Find your certificate of analysis »SmartEnzymes™ for the Glycosylation Charcterization of Glycoproteins
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Performance Activity
Rapid and complete defucosylation of O-glycans on TNFR proteins, outperforming alternative fucosidases across glycoengineered substrates.
Selective removal of α1-2/3/4 fucose for more comprehensive N- and O-glycan characterization.
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