FabRICATOR® Z Fab2 Kit Microspin 5 x 0.5 mg

Immobilized enzyme and affinity resin for below hinge digestion of 5 x 0.5 mg mouse IgG2a and IgG3 and purification of fragments

FabRICATOR Z (IdeZ) is a cysteine protease that digests mouse IgG2a and IgG3 at a specific site below the hinge, generating a homogenous pool of F(ab’)2 and Fc fragments after a two-hour incubation.

FragIT Z kit for creation and isolation of F(ab’)2 and Fc fragments from 5 x 0.5 mg mouse IgG2a. The kit consist of two spin columns – one for fragmentation (FragIT Z column) and one for purification of F(ab’)2 and isolation of Fc fragments.

The FragIT Z column is FabRICATOR Z enzyme immobilized on agarose and the second column has affinity ligands selective for Fc fragments.