SmartEnzymes
- - - Antibody Digestion
    - FabRICATOR^® (IdeS)
      Below hinge digestion of IgG
    - FabALACTICA^® (IgdE)
      Above hinge digestion of human IgG1
    - FabDELLO^™
      Above hinge digestion of human IgG1
    - FabRICATOR^® Z (IdeZ)
      Below hinge digestion of mouse IgG
    - GingisKHAN^® (Kgp)
      Above hinge digestion of human IgG1
    - FabULOUS^™ (SpeB)
      Above hinge digestion of IgG
    - IgASAP^™
      Digestion of IgA
    - IgMBRAZOR^™
      Digestion of IgM
  - - Fusion Protein Digestion
    - GlySERIAS^™
      Hydrolysis of Flexible Linkers
    - Antibody Conjugation
    - GlyCLICK^®
      Site-specific conjugation of IgG
    - TransGLYCIT^™
      Transglycosylation of IgG
    - Proteomics
    - GingisREX^® (RgpB)
      Arginine-specific protein digestion
  - - Glycan Profiling
    - OmniGLYZOR^™
      Hydrolysis of N- and mucin-type O-glycans
    - PNGase F
      Hydrolysis of N-glycans
    - OpeRATOR^®
      O-glycan-specific protein digestion
    - ImpaRATOR^™
      O-glycan-specific protein digestion
    - OglyZOR^®
      Hydrolysis of core 1 O-glycans
    - SialEXO^®
      Hydrolysis of sialic acids
    - FucosEXO^™
      Hydrolysis of α1-2,3,4 fucose
    - GalactEXO^™
      Hydrolysis of β1-3,4 galactose
    - GalNAcEXO^™
      Hydrolysis of α-linked GalNAcs
    - GlycOCATCH^®
      Enrichment of O-glycopeptides
  - - Antibody Deglycosylation
    - GlycINATOR^® (EndoS2)
      Hydrolysis of all Fc N-glycans
    - IgGZERO^® (EndoS)
      Hydrolysis of Fc N-glycans
    - Research Antibodies
    - Anti-FabRICATOR^®
      Detection of the FabRICATOR^® enzyme
    - Anti-FabRICATOR^® Z
      Detection of the FabRICATOR^® Z enzyme
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Genovis / FAQs / Antibody Conjugation / TransGLYCIT / What is the substrate specificity of GlycINATOR?

What is the substrate specificity of GlycINATOR?

GlycINATOR is an IgG specific endoglycosidase that hydrolyzes complex, hybrid and high mannonse type glycans on the conserved Fc site on IgG.