SmartEnzymes Anti-FabRICATOR workflow

Detection of the FabRICATOR® Enzyme

Anti-FabRICATOR (Anti-IdeS) is a family of antibody products for the detection of the FabRICATOR (IdeS) enzyme.

Anti-FabRICATOR is available in five formats. It can be used to detect the IdeS enzyme in Western blot and ELISA assays, for example in preclinical gene therapy applications.

Read more about FabRICATOR (IdeS).
 

  • Sensitive antibody products for detection of the FabRICATOR enzyme
  • Highly purified products with a high affinity to the enzyme
  • Important tool in immunoassay development
  • Amenable to preclinical gene therapy applications
Detects the FabRICATOR (IdeS) enzyme
Source polyclonal: goat
Source monoclonal: mouse
Polyclonal or monoclonal
Concentrations ranging from 0.5 mg/ml to 4 mg/ml

Anti-FabRICATOR® Affinity Purified

Affinity purified goat polyclonal antibody targeting the FabRICATOR enzyme

Anti-FabRICATOR® Affinity Purified Biotin Conjugated

Affinity purified, biotin-conjugated goat polyclonal antibody targeting the FabRICATOR enzyme

Anti-FabRICATOR® Protein G Purified

Protein G-purified goat polyclonal antibody targeting the FabRICATOR enzyme

Anti-FabRICATOR® Monoclonal

Purified mouse monoclonal antibody targeting the FabRICATOR enzyme

Anti-FabRICATOR® Monoclonal Biotin Conjugated

Purified, biotin-conjugated mouse monoclonal antibody targeting the FabRICATOR enzyme

About Anti-FabRICATOR®

The Anti-FabRICATOR products are sensitive reagents for detecting the FabRICATOR (IdeS) enzyme.

FabRICATOR (IdeS) is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments. FabRICATOR has no other known substrate besides IgG, and is cloned from Streptococcus pyogenes and expressed in E. coli.

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