OpeRATOR Lyophilized 2000 units

Lyophilized enzyme for digestion of 2 mg mucin-type O-glycoproteins and peptides

OpeRATOR is an O-glycan-specific protease that digests proteins carrying core 1 O-glycans, N-terminally of the glycosylated (core 1) Ser and Thr residues.

Lyophilized OpeRATOR for digestion of 2 mg glycoprotein.
OpeRATOR is an O-glycan specific endoprotease that digests the amino acid backbone N-terminally of the S/T residue.

The enzyme is active on native glycoproteins and does not require denaturing of the glycoprotein. It is active on O-glycan proteins with and without sialic acids, but the activity is higher on proteins where sialic acids have been removed. For this reason, a vial of SialEXO is included. Both OpeRATOR and SialEXO is reconstituted by addition of water.