FabRICATOR® Immobilized Midispin 1-10 mg

Immobilized enzyme for below hinge digestion of 1-10 mg IgG in spin columns

FabRICATOR (IdeS) is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.

One FragIT Microspin column for digestion of up up 10 mg IgG.

FragIT is FabRICATOR enzyme immobilized on agarose allowing for antibody subunit fragmentation without contaminating the final preparation with FabRICATOR enzyme.