FabRICATOR® Fab2 Kit Maxispin 100 mg
Immobilized enzyme and affinity resin for below hinge digestion of 100 mg IgG and purification of fragments
FabRICATOR (IdeS) is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.
FragIT kit for creation and isolation of F(ab’)2 and Fc fragments from up to 100 mg IgG. The kit consist of two spin columns – one for fragmentation (FragIT column) and one for purification of F(ab’)2 and isolation of Fc fragments.
The FragIT column is FabRICATOR enzyme immobilized on agarose and the second column has affinity ligands selective for Fc fragments.
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