Anti-FabRICATOR® – Detection of the FabRICATOR® Enzyme

Anti-FabRICATOR (Anti-IdeS) is a family of antibody products for the detection of the FabRICATOR (IdeS) enzyme.

Anti-FabRICATOR antibody products are available in five formats. They can be used to detect the IdeS enzyme in ELISA assays, for example in preclinical gene therapy applications.

Read more about FabRICATOR (IdeS).

Why Anti-FabRICATOR®?

  • Sensitive antibody products for detection of the FabRICATOR enzyme
  • Highly purified products with a high affinity to the enzyme
  • Important tool in immunoassay development
  • Amenable to preclinical gene therapy applications
  • Target

    Detects the FabRICATOR (IdeS) enzyme

  • Source

    Source polyclonal: goat Source monoclonal: mouse

  • Concentration

    Concentrations ranging from 0.5 mg/ml to 1 mg/ml

  • Format

    Polyclonal or monoclonal

Product Formats

About Anti-FabRICATOR®

The Anti-FabRICATOR antibody products are sensitive reagents for detecting the FabRICATOR (IdeS) enzyme.

FabRICATOR (IdeS) is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments. FabRICATOR has no other known substrate besides IgG, and is cloned from Streptococcus pyogenes and expressed in E. coli.

Resources

FAQ and Support

No, the monoclonal for biotinylation is produced by another clone of mouse hybridoma.