FabRICATOR® Low Endotoxin 5000 units

Lyophilized enzyme with low levels of endotoxin for below hinge digestion of 5 mg IgG

FabRICATOR (IdeS) is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.

FabRCATOR LE (IdeS) enzyme lyophilized for digestion of 5 mg of antibody. This product formulation has low levels of endotoxins (<0.04 EU /vial). The product is reconstituted by addition of water. FabRICATOR (IdesS) is a unique protease that cleaves IgGs and Fc-fusions at one single amino acid position in the lower hinge region generating Fc and F(ab')2 fragments.