IgGZERO Immobilized Maxispin 10-100 mg

Immobilized enzyme for deglycosylation of 10-100 mg IgG in spin columns

IgGZERO (EndoS) is an IgG-specific endoglycosidase hydrolyzing complex N-glycans at the Fc N-glycosylation sites.

1 columns for deglycosylation of 10 – 100 mg of IgG. The column contains IgGZERO (EndoS) enzyme immobilized on agarose. IgGZERO deglycosylate complex N-glycans on Fc

FAQ and Support

In both products the enzyme is immobilized on agarose beads for IgG-specific hydrolysis of the Fc glycans to the innermost GlcNAc. IgGZERO Immobilized contains IgGZERO (EndoS) and GlycINATOR Immobilized contains GlycINATOR (EndoS2). The GlycINATOR enzyme has much higher enzymatic activity for high mannose and some bisected and hybrid glycans that can occur on mAbs.