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Product Information
All SmartEnzymes
Application Notes
Videos
FabRICATOR
FabRICATOR (IdeS) is a cysteine protease that digests antibodies at a specific site below the hinge, generating a homogenous pool of F(ab')2 and Fc/2 fragments. Watch the movie of how FabRICATOR works here.
GlyCLICK
GlyCLICK is a site-specific conjugation technology for IgG using enzymatic remodeling of the Fc-glycans and click-chemistry. It facilitates site-specific labeling of antibodies in a range of applications, for example imaging and ADC development. Watch the movie of how GlyCLICK works here.
OpeRATOR
OpeRATOR is an O-glycan specific protease that digests proteins carrying mucin-type O-glycans N-terminally of serine and threonine glycosylation sites. Watch the movie of how OpeRATOR works here.
FabRICATOR® MagIC
Dan Bach Kristensen from Symphogen A/S presents an evaluation of FabRICATOR MagIC for automated digestion of antibodies and middle-level analysis of complex antibody mixtures. Watch the entire presentation here.
Posters
GlyCLICK
Robust Generation of Site-specific and Homogeneous Antibody Conjugates using GlyCLICK®
World ADC, 2019
FabRICATOR-HPLC
An Automated Workflow for Analysis of Monoclonal Antibody Subunits
Analytical Technologies Europe (CASSS), 2019
GlycINATOR
Therapeutic Antibodies Trimmed with GlycINATOR® Loses Antibody-Dependent Cell-mediated Cytotoxicity
Antibody Industrial Symposium, 2018
Immobilized SialEXO
Complete and Rapid Desialylation of Therapeutic Glycoproteins using Immobilized SialEXO
Antibody Engineering & Therapeutics, 2019
GlyCLICK
Robust Generation of Site-specific and Homogeneous Antibody Conjugates using GlyCLICK®
World ADC, 2019
Site-specific O-glycan Analysis using a Novel O-glycan Protease and LC-MS/MS
PEGS Summit Europe, 2017
OpeRATOR and GlycOCATCH
FabRICATOR-HPLC
An Automated Workflow for Analysis of Monoclonal Antibody Subunits
Analytical Technologies Europe (CASSS), 2019
FabALACTICA (IgdE)
FabALACTICA Generates Pure and Homogeneous mAb Subunits that Facilitate 2D-NMR Spectroscopy Analysis
Festival of Biologics, 2019
Characterization of a Novel Protease (IgdE) for Above Hinge Antibody Subunit Generation
Analytical Technologies Europe (CASSS), 2017 and PEGS US, 2017
OpeRATOR, OglyZOR, SialEXO
Novel Enzymes for O-glycan Analysis
Analytical Technologies Europe (CASSS) 2018
OglyZOR, SialEXO
Complete N- and O-Deglycosylation of Biopharmaceuticals
PEGS, 2019
GlycINATOR
Therapeutic Antibodies Trimmed with GlycINATOR® Loses Antibody-Dependent Cell-mediated Cytotoxicity
Antibody Industrial Symposium, 2018
GingisREX (RgpB)
RgpB – an Arginine Specific Protease with Applications in Proteomics
Analytical Technologies Europe (CASSS), 2016 and US HUPO, 2016
FabRICATOR in Middle-Down MS
GingisKHAN (KGP)
Initial Characterization of a Novel Cysteine Protease for Antibody Sub Unit Analysis
Analytical Technologies Europe (CASSS), 2015
SmartEnzymes & HPLC
Rapid and Simple Determination of PTMs in Monoclonal Antibodies using an Enzymatic HPLC Approach
Biotherapeutics Analytical Summit, 2014
SmartEnzymes for Rapid LC/MS
Highly Specific Enzymes for Rapid LC/MS Analysis of Therapeutic Antibody Products
ASMS, 2014
Instructions
EXOglycosidases
GalactEXO®
SialEXO®
GalNAcEXO™
FabRICATOR® Z
FabULOUS®
GingisKHAN®
IgG Glycosidases
GlycINATOR®
O-glycans
GlycOCATCH®
OglyZOR®
OpeRATOR®
SialEXO®
Specifications
FabRICATOR®
- FabRICATOR 96x100 units
- FabRICATOR 5000 units
- FabRICATOR 2000 units
- FabRICATOR 8x100 units
- FabRICATOR 5x5000 units
- FragIT Microspin
- FragIT Midispin
- FragIT Maxispin
- FragIT kit Microspin 0.5 mg
- FragIT kit Microspin 5 x 0.5 mg
- FragIT kit Microspin 10 x 0.5 mg
- FragIT kit Midispin 1-10 mg
- FragIT kit Maxispin 10-100 mg
- FabRICATOR LE, 2000 units
- FabRICATOR LE, 5000 units
- FabRICATOR Validation Kit
- FabRICATOR-HPLC
- FabRICATOR MagIC
- Anti-FabRICATOR
FabULOUS®
EXOglycosidases
GalactEXO®
SialEXO®
GalNAcEXO™
O-glycans
GlycOCATCH®
OglyZOR®
OpeRATOR®
SialEXO®
Safety Data Sheets
FabRICATOR® Z
FabULOUS®
GingisKHAN®
EXOglycosidases
GalactEXO®
SialEXO®
GalNAcEXO™
O-glycans
GlycOCATCH®
OglyZOR®
OpeRATOR®
SialEXO®
Certificate of Analysis
- Anti-FabRICATOR A3A1-12E09K
- Anti-FabRICATOR A3AF1-12E09K
- Anti-FabRICATOR A3AF1-7C17H
- CaptureSelect CH1 140729-02
- CaptureSelect CH1 141201-02-02
- CaptureSelect CH1 141201-02-03
- CaptureSelect CH1 141201-02
- CaptureSelect CH1 150922-01
- CaptureSelect CH1 180116-01-01
- CaptureSelect CH1 180116-01-02
- CaptureSelect CH1 180116-01-03
- CaptureSelect CH1 180116-01-04
- CaptureSelect CH1 180116-01-05
- CaptureSelect Fc 160629-01
- CaptureSelect Fc 170322-01-02
- CaptureSelect Fc 170322-01-03
- CaptureSelect Fc 170322-01-04
- CaptureSelect Fc 170322-01-05
- CaptureSelect Fc 170322-01
- CaptureSelect Fc 180301-01-01
- CaptureSelect Fc 180301-01-02
- CaptureSelect Fc 180301-01-03
- CaptureSelect Fc 180301-01-04
- CaptureSelect Fc 180301-01-05
- CaptureSelect Fc 180301-01-06
- CaptureSelect Fc 180301-01-07
- CaptureSelect Fc 180301-01-08
- CaptureSelect Fc 180301-01-09
- CaptureSelect Fc 180301-01-10
- CaptureSelect Fc 181120-01-01
- CaptureSelect Fc 181120-01-02
- CaptureSelect Fc 181120-01-03
- CaptureSelect Fc 181120-01-04
- CaptureSelect Fc 181120-01-05
- CaptureSelect Fc 181120-01-06
- CaptureSelect Fc 181120-01-07
- CaptureSelect Fc 181120-01-08
- CaptureSelect Fc 181120-01-09
- CaptureSelect Fc 181120-01-10
- CaptureSelect Fc 181120-01-11
- CaptureSelect Fc 190411-01-01
- CaptureSelect Fc 190411-01-02
- CaptureSelect Fc 190411-01-03
- CaptureSelect Fc 190411-01-04
- CaptureSelect Fc 191003-01-01
- CaptureSelect Fc 191003-01-02
- CaptureSelect LC-kappa 160531-01
- CaptureSelect LC-kappa 170220-01-02
- CaptureSelect LC-kappa 170220-01-03
- CaptureSelect LC-kappa 170220-01-04
- CaptureSelect LC-kappa 170220-01
- CaptureSelect LC-kappa 180103-01-01
- CaptureSelect LC-kappa 190306-01-01
- FabALACTICA 2000 units A0AG1-11J05G
- FabALACTICA 2000units A0AG1-10D07B
- FabALACTICA 2000units A0AG1-10D11B
- FabALACTICA 2000units A0AG1-10D21B
- FabALACTICA 2000units A0AG1-10H31B
- FabALACTICA 2000units A0AG1-12D12B
- FabALACTICA 2000units A0AG1-13F04B
- FabRICATOR-HPLC A0FRC-11G02K
- FabRICATOR-HPLC A0FRC-11I27K
- FabRICATOR-HPLC A0FRC-12C29G
- FabRICATOR-HPLC A0FRC-12K28G
- FabRICATOR-HPLC A0FRC-13F12L
- FabRICATOR 2000u A0FR1-12B20B
- FabRICATOR 2000u A0FR1-12K20E
- FabRICATOR 2000units A0FR1-10D05H
- FabRICATOR 2000units A0FR1-11E30H
- FabRICATOR 2000units A0FR1-13H07H
- FabRICATOR 2000units A0FR1-9F22F
- FabRICATOR 5000u A0FR1-12K26E
- FabRICATOR 5000units A0FR1-11E30H
- FabRICATOR 5000units A0FR1-12B04E
- FabRICATOR 800units A0FR1-11C19E
- FabRICATOR 800units A0FR1-11F11E
- FabRICATOR 9600units A0FR1-11C19E
- FabRICATOR 9600units A0FR1-11F11E
- FabRICATOR A0FR1-10C09H
- FabRICATOR A0FR1-10C17H
- FabRICATOR A0FR1-10E30H
- FabRICATOR A0FR1-11A25H
- FabRICATOR A0FR1-12B07E
- FabRICATOR A0FR1-12J22E
- FabRICATOR A0FR1-9H31H
- FabRICATOR LE 2000units A0FR8-11A17B
- FabRICATOR LE 2000units A0FR8-13H03H
- FabRICATOR LE 2000units A0FR8-7J16G
- FabRICATOR LE 5000u A0FR8-12I04E
- FabRICATOR LE 5000units A0FR8-11A17B
- FabRICATOR LE 5000units A0FR8-13G29H
- FabRICATOR LE 5000units A0FR8-7J16G
- FabRICATOR LE A0FR8-13I21B
- FabRICATOR MagIC A0FRM-13D27B
- FabRICATOR MagIC A0FRM-13G02B
- FabRICATOR ValidationKit A0FR1-9F22F A0FR1-10C17H A0FR1-10D05H
- FabRICATOR Validation Kit 2019-01-15
- FabRICATOR Z 2000units A0FRZ-11F28B
- FabRICATOR Z 2000units A0FRZ-12E17L
- FabRICATOR Z 2000units A0FRZ-8E06H
- FabRICATOR Z 2000units A0FRZ-8F29H
- FabRICATOR Z 2000units A0FRZ-9J30H
- FabULOUS 2000 units A0PU1-11K09B
- FabULOUS 2000u A0PU1-13D29P
- FabULOUS 2000units A0PU1-10D05B
- FabULOUS 2000units A0PU1-10H25H
- FabULOUS 2000units A0PU1-12L20P
- FabULOUS 2000units A0PU1-13I03H
- FabULOUS 2000units A0PU1-9D29G
- FabULOUS 2000units A0PU1-9F17G
- FragIT Maxi A0FR6-12B15G
- FragIT Maxispin A0FR6-10E30B
- FragIT Maxispin A0FR6-10G26H
- FragIT Maxispin A0FR6-10K09H
- FragIT Maxispin A0FR6-11D23E
- FragIT Maxispin A0FR6-11H08B
- FragIT Maxispin A0FR6-11I11B
- FragIT Maxispin A0FR6-11J23B
- FragIT Maxispin A0FR6-11K14B
- FragIT Maxispin A0FR6-12A22G
- FragIT Maxispin A0FR6-12E23B
- FragIT Maxispin A0FR6-12G29H
- FragIT Maxispin A0FR6-12J15E
- FragIT Maxispin A0FR6-12K15G
- FragIT Maxispin A0FR6-12K21G
- FragIT Maxispin A0FR6-13B05G
- FragIT Maxispin A0FR6-13C31B
- FragIT Maxispin A0FR6-13G29G
- FragIT Maxispin A0FR6-13I29G
- FragIT Maxispin A0FR6-9G07G
- FragIT Maxispin A0FR6-9K29H
- FragIT Micro A0FR6-12B15G
- FragIT Microspin A0FR6-10E30B
- FragIT Microspin A0FR6-10G26H
- FragIT Microspin A0FR6-10K09H
- FragIT Microspin A0FR6-11D23E
- FragIT Microspin A0FR6-11H08B
- FragIT Microspin A0FR6-11I11B
- FragIT Microspin A0FR6-11J23B
- FragIT Microspin A0FR6-11K14B
- FragIT Microspin A0FR6-12A22G
- FragIT Microspin A0FR6-12E23B
- FragIT Microspin A0FR6-12G29H
- FragIT Microspin A0FR6-12J15E
- FragIT Microspin A0FR6-12K15G
- FragIT Microspin A0FR6-12K21G
- FragIT Microspin A0FR6-13B05G
- FragIT Microspin A0FR6-13C31B
- FragIT Microspin A0FR6-13G29G
- FragIT Microspin A0FR6-13I29G
- FragIT Microspin A0FR6-9G07G
- FragIT Microspin A0FR6-9K29H
- FragIT Midi A0FR6-12B15G
- FragIT Midispin A0FR6-10E30B
- FragIT Midispin A0FR6-10G26H
- FragIT Midispin A0FR6-10K09H
- FragIT Midispin A0FR6-11D23E
- FragIT Midispin A0FR6-11H08B
- FragIT Midispin A0FR6-11I11B
- FragIT Midispin A0FR6-11J23B
- FragIT Midispin A0FR6-11K14B
- FragIT Midispin A0FR6-12A22G
- FragIT Midispin A0FR6-12E23B
- FragIT Midispin A0FR6-12G29H
- FragIT Midispin A0FR6-12J15E
- FragIT Midispin A0FR6-12K15G
- FragIT Midispin A0FR6-12K21G
- FragIT Midispin A0FR6-13B05G
- FragIT Midispin A0FR6-13C31B
- FragIT Midispin A0FR6-13G29G
- FragIT Midispin A0FR6-13I29G
- FragIT Midispin A0FR6-9G07G
- FragIT Midispin A0FR6-9K29H
- FragIT Z A0FZ6-10E17B
- FragIT Z A0FZ6-11A09B
- FragIT Z A0FZ6-12E02E
- FragIT Z A0FZ6-13B18P
- FragIT Z A0FZ6-13J28P
- FragIT Z A0FZ6-8E19G
- FragIT Z A0FZ6-8G01G
- FragIT Z A0FZ6-9H24G
- FragIT Z Microspin A0FZ6-11H07B
- GalNAcEXO G1NA1-13I16E
- GalactEXO G1GM1-13F18P
- GingisKHAN 2000u B0GKH-12C05B
- GingisKHAN 2000u B0GKH-12F27B
- GingisKHAN 2000u B0GKH-13E11B
- GingisKHAN 2000u B0GKH-13I11H
- GingisKHAN 2000units B0GKH-10C24B
- GingisKHAN 2000units B0GKH-11B09H
- GingisKHAN 2000units B0GKH-11D27B
- GingisKHAN 2000units B0GKH-9I30H
- GingisKHAN 2000units B0GKH-9J10G
- GingisKHAN B0GKH-12B07E
- GingisKHAN Reducing Agent B0CYS-10E03H
- GingisKHAN Reducing Agent B0CYS-11C13H
- GingisKHAN Reducing Agent B0CYS-11E15E
- GingisKHAN Reducing Agent B0CYS-11E21E
- GingisKHAN Reducing Agent B0CYS-11E25E
- GingisKHAN Reducing Agent B0CYS-12B14E
- GingisKHAN Reducing Agent B0CYS-12H19E
- GingisKHAN Reducing Agent B0CYS-13C10P
- GingisKHAN Reducing Agent B0CYS-13J13P
- GingisKHAN Reducing Agent B0CYS-9F21H
- GingisKHAN Reducing Agent B0CYS-9L07H
- GingisREX 5ug B0GRX-11B06B
- GingisREX 5ug B0GRX-11E07B
- GingisREX 5ug B0GRX-9D07H
- GingisREX 5ug B0GRX-9D26H
- GingisREX 5ug B0GRX-9K16H
- GingisREX B0GRX-12G09H
- GingisREX B0GRX-13E15B
- GingisREX B0GRX-13I24H
- GlyCLICK AlexaFluor488 DIBO 1881100
- GlyCLICK AlexaFluor488 DIBO 1918471
- GlyCLICK AlexaFluor488 DIBO 2125601
- GlyCLICK AlexaFluor488 DIBO 2210320
- GlyCLICK AlexaFluor 555 DIBO 2218564
- GlyCLICK AlexaFluor 647 DIBO 2218567
- GlyCLICK Azide Activation Kit 0.25mg L1AZ1-12F28M
- GlyCLICK Azide Activation Kit 0.25mg L1AZ1-12G22H
- GlyCLICK Azide Activation Kit 0.25mg L1AZ1-12K26H
- GlyCLICK Azide Activation Kit 0.25mg L1AZ1-13C10H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-11B15H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-11E25H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-12J15H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-13B05H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-13G29H
- GlyCLICK Azide Activation Kit 10mg L1AZ1-13K17H
- GlyCLICK Azide Activation Kit 250ug L1AZ1-10C27H
- GlyCLICK Azide Activation Kit 250ug L1AZ1-10F01H
- GlyCLICK Azide Activation Kit 250ug L1AZ1-11D19H
- GlyCLICK Azide Activation Kit 250ug L1AZ1-13I08H
- GlyCLICK Azide Activation Kit 2mg L1-AZ1-12J07N
- GlyCLICK Azide Activation Kit 2mg L1AZ1-13K10H
- GlyCLICK Azide Activation Kit 2mg L1AZ1-12K28H
- GlyCLICK Azide Activation Kit 2mg L1AZ1-13A14H
- GlyCLICK Azide Activation Kit 2mg L1AZ1-13E12H
- GlyCLICK Azide Activation Kit 2mg L1AZ1-13G22H
- GlyCLICK Biotin DIBO 1881098
- GlyCLICK Biotin DIBO 2125594
- GlyCLICK DFO Chelator DIBO Lot1
- GlycINATOR 2000u A0GL1-12K15P
- GlycINATOR 2000units A0GL1-10D18B
- GlycINATOR 2000units A0GL1-10L11H
- GlycINATOR 2000units A0GL1-8I29G
- GlycINATOR LE 2000units A0GL8-9D04H
- GlycOCATCH 200 ug G1OC6-11J29E
- GlycOCATCH 200ug G1OC6-11A24H
- IgGZERO 1000units A0IZ1-11H21E
- IgGZERO 1000units A0IZ1-9J19H
- IgGZERO 5000units A0IZ1-11H21E
- IgGZERO 5000units A0IZ1-12I02E
- IgGZERO 5000units A0IZ1-9J19H
- IgGZERO LE 2000units A0IZ8-9D04H
- IgGZero 5000units A0IZ1-13H20H
- Immobilized FabALACTICA A0AG6-11F07E
- Immobilized FabALACTICA Maxispin A0AG6-10K27E
- Immobilized FabALACTICA Maxispin A0AG6-11E15B
- Immobilized FabALACTICA Maxispin A0AG6-11H09B
- Immobilized FabALACTICA Maxispin A0AG6-12I26B
- Immobilized FabALACTICA Maxispin A0AG6-13F02B
- Immobilized FabALACTICA Microspin A0AG6-10J26E
- Immobilized FabALACTICA Microspin A0AG6-10K27E
- Immobilized FabALACTICA Microspin A0AG6-11B13B
- Immobilized FabALACTICA Microspin A0AG6-11E15B
- Immobilized FabALACTICA Microspin A0AG6-11F07E
- Immobilized FabALACTICA Microspin A0AG6-11H09B
- Immobilized FabALACTICA Microspin A0AG6-11J31G
- Immobilized FabALACTICA Microspin A0AG6-11K28B
- Immobilized FabALACTICA Microspin A0AG6-12C20B
- Immobilized FabALACTICA Microspin A0AG6-12L02B
- Immobilized FabALACTICA Microspin A0AG6-13C05B
- Immobilized FabALACTICA Midispin A0AG6-10K27E
- Immobilized FabALACTICA Midispin A0AG6-11B13B
- Immobilized FabALACTICA Midispin A0AG6-11E15B
- Immobilized FabALACTICA Midispin A0AG6-11H09B
- Immobilized FabALACTICA Midispin A0AG6-13F02B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-11J03B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-11J31G
- Immobilized FabALACTICA Midispin Maxispin A0AG6-11K28B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-12C20B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-12L02B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-13C05B
- Immobilized FabALACTICA Midispin Maxispin A0AG6-13H26B
- Immobilized FabALCATICA Microspin A0AG6-13F02B
- Immobilized FabALCATICA Microspin A0AG6-13H26B
- Immobilized GalNAcEXO G1NA6-13I17E
- Immobilized GalactEXO G1GM6-13I16P
- Immobilized GlycINATOR A0GL6-10C21H
- Immobilized GlycINATOR A0GL6-10D19H
- Immobilized GlycINATOR A0GL6-10J30E
- Immobilized GlycINATOR A0GL6-11B04H
- Immobilized GlycINATOR A0GL6-11K27B
- Immobilized GlycINATOR A0GL6-12F13E
- Immobilized GlycINATOR A0GL6-12K28B
- Immobilized GlycINATOR A0GL6-13A14B
- Immobilized GlycINATOR A0GL6-13B27P
- Immobilized GlycINATOR A0GL6-13C04B
- Immobilized GlycINATOR Microspin A0GL6-10B27H
- Immobilized GlycINATOR Microspin A0GL6-9J04H
- Immobilized SialEXO G1SM6-12L05B
- Immobilized SialEXO G1SM6-12L09B
- Immobilized SialEXO G1SM6-13B11B
- Immobilized SialEXO G1SM6-13J15B
- OglyZOR 2000 units G1OG1-11K20E
- OglyZOR 2000units G1OG1-10D25E
- OglyZOR 2000units G1OG1-10H09E
- OglyZOR 2000units G1OG1-11H03E
- OpeRATOR 2000 units G1OP1-11K28E
- OpeRATOR 2000units G1OP1-10E19E
- OpeRATOR 2000units G1OP1-11A11E
- OpeRATOR 200units G1OP1-10E19E
- OpeRATOR 200units G1OP1-11D20E
- SialEXO 2000units G1SM1-10E16E
- SialEXO 2000units G1SM1-11G31E
- SialEXO 2000units G1SM1-11H01E
- SialEXO 2000units G1SM1-13B04P
- SialEXO 200u G1SM1-12L17B
- SialEXO 200units G1SM1-11C06H
- SialEXO 23 500u G1SD2-12E15E
- SialEXO 23 500u G1SD2-13A31P
- deGlycIT A0IZ6-10D19H
- deGlycIT A0IZ6-10L07E
- deGlycIT A0IZ6-8B06G
- deGlycIT A0IZ6-9H09G
- deGlycIT Microspin A0IZ6-11I04B
- deGlycIT Microspin A0IZ6-13C25B
- deGlycIT Microspin A0IZ6-13H18P
- deGlycIT Midispin Maxispin A0IZ6-11I04B
- deGlycIT Midispin Maxispin A0IZ6-13C25B
- deGlycIT Midispin Maxispin A0IZ6-13H18P