Genovis / SmartEnzymes / Resources

Product Information

Download the Genovis' Book of Applications and other product information

Instructions

Download the instruction for the product you are interested in

Specifications

Specifications for every Genovis product

Certificate of Analysis

Find the certificate of analysis for your Genovis product

Product Information

Antibody LC-MS Analysis

GlySERIAS

Hydrolysis of Flexible Linkers

OmniGLYZOR

TransGLYCIT

FabDELLO

GlyCLICK

Application Notes

OpeRATOR

Automated O-glycopeptide Profile Monitoring of
Therapeutic Proteins using OpeRATOR in Combination with LC-MS

FabRICATOR MagIC

Automated Middle-level Analysis of Therapeutic mAbs in Complex Protein Samples

FabRICATOR & GlycINATOR

A Rapid LC-MS Assay for Monitoring of mAb Oxidation at the Subunit Level

FabALACTICA

Paired Glycan Analysis of mAbs using FabALACTICA® Digestion and LC-MS

OpeRATOR

Determination of O-glycan sites by OpeRATOR® digestion and LC-MS

FabRICATOR HPLC

Automated Middle-level Antibody Analysis using On-column FabRICATOR Digestion with LC-MS

FabRICATOR

Antibody Fc Glycan Analysis by FabRICATOR® Digestion and LC-MS

Videos

FabRICATOR

FabRICATOR (IdeS) is a cysteine protease that digests antibodies at a specific site below the hinge, generating a homogenous pool of F(ab')2 and Fc/2 fragments. Watch the movie of how FabRICATOR works here.

GlyCLICK

GlyCLICK is a site-specific conjugation technology for IgG using enzymatic remodeling of the Fc-glycans and click-chemistry. It facilitates site-specific labeling of antibodies in a range of applications, for example imaging and ADC development. Watch the movie of how GlyCLICK works here.

OpeRATOR

OpeRATOR is an O-glycan specific protease that digests proteins carrying mucin-type O-glycans N-terminally of serine and threonine glycosylation sites. Watch the movie of how OpeRATOR works here.

FabRICATOR® MagIC

Dan Bach Kristensen from Symphogen A/S presents an evaluation of FabRICATOR MagIC for automated digestion of antibodies and middle-level analysis of complex antibody mixtures. Watch the entire presentation here.

Posters

Glycan Profiling

Enzymatic Tools for the Structural Characterization
of Glycoproteins
EMBO Workshop, 2024

SmartEnzymes

Enzymatic Tools for Generation of Homogeneous Antibody Fragments - from High-throughput Screening to Manufacturing Scale
PEGS Europe, 2023

PNGase F

PNGase F on Magnetic Beads for Automated High-throughput Analysis of Glycoprotein Therapeutics
CASSS AT Europe, 2023

TransGLYCIT

Fast and Efficient Evaluation of the Impact of lgG Fc N-glycan Structure on Effector Functions
PEGS Europe, 2023

GlyCLICK

Enzymatic Strategies for Robust ADC Generation and Streamlined Analysis
ADC Analytical Development Summit, 2024