SialEXO 23

470.00

SialEXO 23 specifically hydrolyzes α2-3 sialic acids

470.00
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Description

SialEXO 23 contains a sialidase acting specifically on α2-3 linked sialic acids. The SialEXO 23 enzyme hydrolyzes all α2-3 sialic acids from N- and O-glycosylated proteins and peptides as well as released glycans. SialEXO23 is available as lyophilized powder for α2-3-specific desialylation of 0.5 mg of sialylated glycoproteins.

Detailed Information

Application

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Product Composition

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Digestion Site

Specificity

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Reaction Conditions

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Buffer Compatibility

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Unit Definition

FAQs

Yes, SialEXO displays activity on sialic acids with α2-3, α2-6 and α2-8 linked bonds of both N- and O-glycans.

Yes, SialEXO can be incubated together with OpeRATOR and/or OglyZOR in 20 mM Tris pH 6.8.

Yes, both enzymes are active under neutral conditions, preferably use 20 mM Tris pH 7.

Yes, SialEXO contains a 6x His-tag.

No, SialEXO works both on glycoproteins in native conditions but can also be used on denatured proteins after buffer exchange.

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