SmartEnzymes
- - - Antibody Digestion
    - FabRICATOR^® (IdeS)
      Below hinge digestion of IgG
    - FabALACTICA^® (IgdE)
      Above hinge digestion of human IgG1
    - FabDELLO^™
      Above hinge digestion of human IgG1
    - FabRICATOR^® Z (IdeZ)
      Below hinge digestion of mouse IgG
    - GingisKHAN^® (Kgp)
      Above hinge digestion of human IgG1
    - FabULOUS^™ (SpeB)
      Above hinge digestion of IgG
    - IgASAP^™
      Digestion of IgA
    - IgMBRAZOR^™
      Digestion of IgM
  - - Fusion Protein Digestion
    - GlySERIAS^™
      Hydrolysis of Flexible Linkers
    - Antibody Conjugation
    - GlyCLICK^®
      Site-specific conjugation of IgG
    - TransGLYCIT^™
      Transglycosylation of IgG
    - Proteomics
    - GingisREX^® (RgpB)
      Arginine-specific protein digestion
  - - Glycan Profiling
    - OmniGLYZOR^™
      Hydrolysis of N- and mucin-type O-glycans
    - PNGase F
      Hydrolysis of N-glycans
    - OpeRATOR^®
      O-glycan-specific protein digestion
    - ImpaRATOR^™
      O-glycan-specific protein digestion
    - OglyZOR^®
      Hydrolysis of core 1 O-glycans
    - SialEXO^®
      Hydrolysis of sialic acids
    - FucosEXO^™
      Hydrolysis of α1-2,3,4 fucose
    - GalactEXO^™
      Hydrolysis of β1-3,4 galactose
    - GalNAcEXO^™
      Hydrolysis of α-linked GalNAcs
    - GlycOCATCH^®
      Enrichment of O-glycopeptides
  - - Antibody Deglycosylation
    - GlycINATOR^® (EndoS2)
      Hydrolysis of all Fc N-glycans
    - IgGZERO^® (EndoS)
      Hydrolysis of Fc N-glycans
    - Research Antibodies
    - Anti-FabRICATOR^®
      Detection of the FabRICATOR^® enzyme
    - Anti-FabRICATOR^® Z
      Detection of the FabRICATOR^® Z enzyme
- - - View All Products »
Antibodies
BioProcess
Gene Therapy
Services

Genovis / FAQs / Glycan Profiling / OglyZOR / Will OglyZOR leave the N-glycans intact?

Will OglyZOR leave the N-glycans intact?

OglyZOR only works on desialylated O-glycans therefore is a sialidase (SialEXO) included with the product. SialEXO is not O-glycan specific and will therefore desialylate any N-glycans that are present.