Are there any mutated IgG formats that FabRICATOR Xtra LALA cannot digest?

Yes, of the formats we have specifically tested, hIgG1-LALAPG (L234A, L235A, P329G), hIgG1-STR (L234S, L235T, G236R) and hIgG1-L234F, L235E, D265A could not be digested to satisfactory levels using FabRICATOR Xtra LALA. Please refer to footnote 4 in the instructions for use to determine whether your antibody is likely to be suitable for FabRICATOR Xtra LALA digestion.