Immunoglobulin Proteases – Proteases for specific antibody digestion, enabling detailed and reproducible characterization of antibodies, including those with mutated hinges.
Product Formats
FabALACTICA™ Immobilized
Immobilized enzyme for above hinge digestion of human IgG1 in spin columns
Buy productFabRICATOR® Z Lyophilized
Lyophilized enzyme for below hinge digestion of mouse IgG2a and IgG3
Buy productFabALACTICA™ Fab Kit
Immobilized enzyme and affinity resin for above hinge digestion of human IgG1 and purification of Fab fragments
Buy productFabULOUS™ Fab Kit
Lyophilized enzyme and affinity resin for hinge-region digestion of murine IgG and purification of fragments
Buy productFabRICATOR® Z Immobilized
Immobilized enzyme for below hinge digestion of mouse IgG2a and IgG3 in spin columns
Buy productFabRICATOR® Z Fab2 Kit
Immobilized enzyme and affinity resin for below hinge digestion of mouse IgG2a and IgG3 and purification of fragments
Buy product
Applications
Site-specific IgM digestion under physiological conditions, producing homogeneous fragments for precise middle-level LC-MS characterization.
Efficient digestion of hinge-mutated antibodies, generating fragments for comprehensive subunit LC-MS analysis of engineered IgG formats
Performance Activity
Generation and purification of F(ab’)2 and scFc fragments without residual enzyme, enabling rapid preparation of antibody fragments for downstream applications.
Resources
FabRICATOR® Xtra for Below Hinge Characterization of Hinge Mutated Antibodies
Download Scientific Poster
AppNote FabRICATOR® for Glycan Analysis
Download Application Notes
How FabRICATOR® works
Watch video
FAQ and Support
There are not yet any FAQ’s for this product. If you have a technical question, please contact us.
Legal & Disclaimers
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