Native removal of O-glycans and removal of inaccessible N-glycans under denaturing conditions, enables complete glycan analysis of the complex C1-inhibitor
Applications
Explore how our solutions are used across a range of applications. From sample preparation to advanced analysis, you can find insights into how they support different workflows and help address common challenges.
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Robust and reproducible digestion of dulaglutide linkers, separating GLP-1 peptides from the Fc for domain-specific LC-MS analysis of protein modifications
Efficient digestion of multi-domain BiTE molecules, separating the domains for high-quality LC-MS analysis and precise localization of protein modifications
Efficient digestion of hinge-mutated antibodies, generating fragments for comprehensive subunit LC-MS analysis of engineered IgG formats
Efficient analysis of bispecific antibodies, enabling accurate assessment of chain pairing and assembly in Fc-engineered antibody formats
Enhanced cleavage at challenging K–P sites, reducing missed cleavages and enabling more complete, confident peptide identification.
