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exploit FragIT, OglyZOR and SialEXO Simone Nicolardi Leiden University Medical Center GingisKHAN & FabRICATOR assist in-source decay FT-ICR Mass Spectrometry analysis Oliver Krigslund Finsen Laboratory/BRIC, University of Copenhagen GlyCLICK for

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Emmanuelle Leize-Wagner, Yannis-Nicolas François, Middle-level IM-MS and CIU experiments for improved therapeutic immunoglobulin isotype fingerprinting 2020-01-21 Thomas Botzanowski, Oscar Hernandez-Alba, Martine Malissard, Elsa Wagner-Rousset, Evolène Deslignière, Olivier Colas, Jean-François Haeuw,…

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Fluorescent imaging

Indirect detection methods require several incubation steps and secondary antibodies are a potential source of unsolicited background staining due to unspecific binding or cross-reactivity.Site-specific and quantitative conjugation using GlyCLICK enables…

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FabRICATOR MagIC Application

platforms High throughput parallel analysis of antibodies Complete digestion in 10-20 minutes Fast parallel sample preparation with minimal hands-on time Therapeutic antibodies and other IgG-based biopharmaceuticals require careful characterization and…

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GlyCLICK

B. & Qasba, P.K., 2002. Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity. J Biol Chem, 277(23), pp.20833–20839….

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