Immobilized FabALACTICA

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Immobilized FabALACTICA®

The Immobilized FabALACTICA spin columns contain FabALACTICA enzyme covalently coupled to agarose beads, for digestion of human IgG1 without contaminating the final preparation with enzyme.

 

FabALACTICA (IgdE) is a cysteine protease that digests human IgG1 at one specific site above the hinge with no need for reducing conditions or co-factors.

 

 

Detailed Information 

Immobilized FabALACTICA consists of FabALACTICA enzyme immobilized on agarose beads in a convenient spin column format. The spin columns are available for digestion of up to 0.5 mg (Microspin), 10 mg (Midispin) or 100 mg (Maxispin) human IgG1. The smallest columns are available in two different pack sizes, with 2 or 10 columns per pack.

FabALACTICA is a cysteine protease that digests human IgG1 at one specific site above the hinge, generating intact Fab and Fc fragments. The enzyme is active at pH from 6-8 and does not require reducing conditions or co-factors for activity. FabALACTICA is recombinantly expressed in E. coli, contains a His-tag, and the molecular weight is 70 019 Da.

Immobilized FabALACTICA does not require reducing conditions or co-factors for activity. 

Storage and Stability

Immobilized FabALACTICA is supplied in 20% ethanol, shipped cold, and should be stored at +4-8°C upon arrival. Do not freeze the product!

Unit Definition

One spin column contains sufficient FabALACTICA-coupled agarose beads to digest 0.5 mg (Microspin), 10 mg (Midispin), or 100 mg (Maxispin) human IgG1.

 

How to order

To place an order, please visit How to order. Click add to cart to buy online.

Quotations

Please do not hesitate to contact us if you need a quotation or have inquiries on price of bulk quantities.

Documents

FAQ and Support

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Patent and Disclaimer

FabALACTICA®

Aspects of FabALACTICA® technology are encompassed by pending patent applications in the name of Genovis AB. The trademark FabALACTICA® is the property of Genovis AB.

For research use only. Not intended for any animal or human therapeutic or diagnostic use.

©2018 Genovis AB.