FabRICATOR (IdeS) is a cysteine protease that digests IgG and Fc-fusion proteins at a specific site below the hinge region, yielding F(ab’)2 and Fc/2 fragments.
Key Characteristics
FabALACTICA is a cysteine protease that digests human IgG1 at a specific site above the hinge, generating intact Fab and Fc fragments. No reducing agents or co-factors are required for enzymatic activity.
Key Characteristics
GingisKHAN is a cysteine protease that digests human IgG1 at a specific site above the hinge, generating intact Fab and Fc fragments.
Key Characteristics
FabULOUS (SpeB) is a cysteine protease that digests IgG in the hinge region of antibodies from many species and subclasses, including human, mouse, rat and goat.
Key Characteristics
FabRICATOR Z is a cysteine protease that digests mouse IgG2a and IgG3 at a specific site below the hinge.
