



EXOglycosidases
The Genovis product line of exoglycosidases consists of:
SialEXO® – Exoglycosidase hydrolyzing terminal sialic acids.
FucosEXO™ – Exoglycosidase hydrolyzing ɑ1-2,3,4 linked fucose.
GalactEXO™ – Exoglycosidase hydrolyzing terminal galactose.
GalNAcEXO™ - Exoglycosidase hydrolyzing GalNAc residues.
An overview of the enzymes are presented on this page. Please visit the individual product pages for full details on the different exoglycosidases.
“EXOglycosidases for removal of terminal glycans”

SialEXO is a sialidase mix for complete removal of sialic acids from
2 mg native glycoprotein.
Key Characteristics
- Hydrolyzes sialic acids on N- and O-linked glycans
- 2 h reaction
- α2-3, α2-6 and α2-8-linked sialic acids
- Requires no co-factors
FucosEXO is a fucosidases for removal of α1-2,3,4 linked fucose from glycoproteins.
Key Characteristics
- Hydrolyzes ɑ1-2,3,4 linked fucose on native glycoproteins
- 1-2 h incubation
- ɑ1-2,3,4 linked fucose
- No co-factors required
GalactEXO is a β-galactosidase for efficient hydrolysis of galactose residues from N- and O-linked glycans on 2 mg glycoprotein.
Key Characteristics
- Galactosidase hydrolyzing galactose on N- and O-glycoproteins or free oligosaccharides
- 2 h reaction
- β1-3 and β1-4 linked galactose residues
- Requires removal of terminal sialic acids (see SialEXO above)

GalNAcEXO is an α-N-Acetylgalactosaminidase for efficient hydrolysis of GalNAc residues.
Key Characteristics
- α-N-Acetylgalactosaminidase hydrolyzing GalNAcs on O-glycoproteins
- Tn antigen (core GalNAc) and α1-3 terminal GalNAc
- 4 h reaction
- No co-factors required