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EXOglycosidases

The Genovis product line of exoglycosidases consists of:

SialEXO® – Exoglycosidase hydrolyzing terminal sialic acids

GalactEXO™ – Exoglycosidase hydrolyzing terminal galactose

GalNAcEXO™ - Exoglycosidase hydrolyzing GalNAc residues

An overview of the enzymes are presented on this page. Please visit the individual product pages for full details on the different exoglycosidases.

GalactEXO is a β-galactosidase for efficient hydrolysis of galactose residues from N- and O-linked glycans on 2 mg glycoprotein. 

Key Characteristics

  • Hydrolyzes O-glycans on glycoproteins
  • 2-4 h reaction
  • Requires removal of sialic acids using SialEXO® (included)
  • Core 1 and core 3 type O-glycan disaccharides

Enzymes for O-Glycans sialexo

SialEXO is a sialidase mix for complete removal of sialic acids from
2 mg native glycoprotein.

Key Characteristics

  • Hydrolyzes sialic acids on N- and O-linked glycans
  • 2 h reaction
  • Requires no co-factors
  • α2-3, α2-6 and α2-8-linked sialic acids

GalNAcEXO is an α-N-Acetylgalactosaminidase for efficient hydrolysis of GalNAc residues.

Key Characteristics

  • α-N-Acetylgalactosaminidase hydrolyzing GalNAcs on O-glycoproteins
  • Tn antigen (core GalNAc) and α1-3 terminal GalNAc
  • 4 h reaction
  • No co-factors required

EXOglycosidase Products

Legal and Disclaimers

All rights reserved. Genovis products are covered by one or more patents, pending patent applications, trademarks and/or copyrights owned or controlled by Genovis AB.

For more information about commercial rights, please contact Genovis team at info@genovis.com.

Genovis products are intended for research use only. They are not intended to be used for therapeutic or diagnostic purposes in humans or animals.

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