Description
5 columns for delglycosylation of 5 x 0.5 mg of IgG.
The column contains GlycINATOR (EndoS2) enzyme immobilized on agarose. GlycINATOR is an endoglycosidase that rapidly cleaves the N-glycan structure of the Fc domain of IgGs. The N-glycan is cleaved after the first GlcNAc.
GlycINATOR effectively removes high-mannose as well as complex and hybrid Fc-glycans on native IgGs.