Genovis » FragIT Z

Name: FragIT Z
SKU: 9476
Price: 335.00 EUR
Availability: InStock

Description

FragIT Z contains FabRICATOR Z (IdeZ) enzyme immobilized on agarose beads. The immobilized enzyme digests mouse IgG2a and IgG3 at one single amino acid position below the hinge generating Fc and F(ab’)2 fragments. FragIT Z is available in spin columns for the digestion of 0.5 – 5 mg of mouse IgG2a and IgG3 without residual enzyme in the final preparation.

Detailed Information

Application	Antibody Fragmentation, Antibody Characterization
Product Group	FabRICATOR Z
Source/Origin	Cloned form S. equi ssp. zooepidemicus, Produced in E. coli (His-tagged), 36.4 kDa
Product Composition	Immobilized on agarose beads (20% EtOH)
Digestion Site	Below Hinge
Specificity	CPAPNLLG / GPSVF (below the hinge)
Substrates	Monkey IgG, Mouse IgG, Rabbit IgG, Sheep IgG
Reaction Conditions	2 hour reaction at 37°C according to protocol specifications
Digestion Buffers	PBS (pH 6.5)
Buffer Compatibility	A digestion buffer with 50-150 mM NaCl can be used, but digestion time needs to be increased (2-24 h) with increasing NaCl concentration and pH.
Inhibitors	Sensitive to high [NaCl]
Unit Definition	0.1 ml settled resin digests ≥ 95% of 0.5 mg Mouse IgG2a

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FragIT Z Microspin, Digest 2 x 0.5 mg quantity	FragIT Z Microspin, Digest 2 x 0.5 mg (A0-FZ6-010)	€350.00
FragIT Z Microspin, Digest 5 x 0.5 mg quantity	FragIT Z Microspin, Digest 5 x 0.5 mg (A0-FZ6-025)	€800.00
FragIT Z Midispin, Digest 1-10 mg quantity	FragIT Z Midispin, Digest 1-10 mg (A0-FZ6-100)	€1,070.00
FragIT Z Microspin, Digest 10 x 0.5 mg quantity	FragIT Z Microspin, Digest 10 x 0.5 mg (A0-FZ6-050)	€1,330.00

FragIT Z

Description

Detailed Information

FAQs

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