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DNA Transfection

NIMT®FeOfection is a transfection agent based on superparamagnetic nanoparticles with an iron oxide core. The particles are produced with a precise size and a very narrow size distribution and the surface is designed to promote non-covalent binding of DNA and facilitate effective transport of the resulting particle/DNA complexes into cells. NIMT®FeOfection uses nanotechnology to achieve consistently high transfection rates with markedly reduced toxicity.

NIMT®FeOfection Transfection Reagents Offers:

  • NIMT®FeOfection is easy and quick to use
  • High transfection rates - On both adherent and suspension cell lines
  • Low cell toxicity - More stable and less toxic than leading transfection reagents
  • Controlled release of DNA inside cells
  • NIMT®FeOfection can be used for transfection of standard screening cells such as HEK293 as well as more difficult-to-transfect cells such as K562 and Jurkat. NIMT®FeOfection transfection agent offer several features that will simplify your transfection.


    Easy to Use

    NIMT®FeOfection for DNA transfection is very easy and quick to use. Simply mix particles with DNA, incubate and add to cells.



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    No Over Expression of Plasmids

    There is no overexpression of the transfected plasmid due to controlled release of DNA inside the cell. The expression per cell is lower compared to other leading transfection reagents which leads to higher survival rates of cells.

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    Low Toxicity

    NIMT®FeOfection is mild to cells and gives high survival rates. The transfection reagent can be used on all kinds of cells, even to cells that are sensitive to other transfection reagents.

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    Stable and Uniform Nano Particles

    NIMT®FeOfection consists of highly uniform and stable nanoparticles with a lipid coating. The precisely controlled production gives the particles a very narrow size distribution.

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    Possibility of Long Incubation Times of Complexes

    The uniform size of the particles gives the ability to incubate transfection complexes a long time. The long incubation time of the complexes is useful in high throughput applications.

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    The Magnetic Core can be Traced

    The iron oxide core gives the unique ability to track transfected cells with MRI. Transfect cells ex vivo, transplant and follow the cells with MRI.

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    Related Products
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    Product Folder
    Simplify Transfection with NIMT®FeOfection.pdf
    Related Applications

    Learn more about NIMT®FeOfection and RNAi here.
    Learn more about Imaging & Labeling here.

    Cell Lines

    Click here to find a list with cell lines that have tested with NIMT®FeOfection|YELLOW.

    Questions?

    Find our FAQ here.  Don't hestiate to contact us at support _ genovis.com (inster @ in _ space) if you have further questions.



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