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Preclinical MR studies and Multimodal Imaging

Genovis has developed a new category of nanoparticles that can be used as contrast agent in more than one type of medical imaging technique such as MRI, PET, SPECT and optical imaging. Compared to commercially available T2-contrast agents used in clinical applications FeOdots have a higher relaxivity and a prolonged blood circulation time. This provides researchers with biocompatible particles with high performance in MRI applications.


Genovis offers

• Custom made superparamagnetic nanoparticles.
• Preclinical MR studies where proof of concept of new clinical products can be evaluated without the high costs associated with clinical MR.
• Complete MRI studies, including study design, in vivo and in vitro model development.
• Longitudinal studies where the progression of a disease can be followed over time.
• Professional assistance with theoretical questions and issues concerning MR imaging. 

NIMT® FeOdots - superparamagnetic nanoparticles for biomedicine & biotechnology

• Detect via MRI and optionally by optical imaging and PET/SPECT.
• Ultra stable PEG-coating allows for use in complex biological fluids without aggregation or unspecific interactions.
• Stable for several weeks in vivo without bleaching enables long-term detection via MRI.
• No cell toxicity.

NIMT® FeOlabel - Intracellular magnetic labeling of cells has never been easier

• Detect labeled cells via fluorescent microscopy and MRI.
• Separate labeled cells via magnetic separation.
• Stable for several weeks in vivo without bleaching enables long-term detection via MRI.
• Low cell toxicity.

App note using NIMT®FeOdots
Following cell migration in rat brain using NIMT®FeOdot PEG-amine.
App note using NIMT®FeOlabel
Following disease progression using NIMT® FeOlabel.
Imaging Services
Genovis offers complete MRI studies to clients, including study design, in vivo and in vitro model development. We also offer expertise help with theoretical questions and issues concerning MR imaging.
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The NIMT® FeOdot platform
Genovis offers extensive service and knowledge surrounding our magnetic nanoparticle platform thereby providing our customer with custom made selection of particles and imaging service.
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Magnetic labelling of cells
Label your cells with magnetic nano-particles and track the cells using MRI.

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